Colchicine-induced pancreatitis in an elderly patient with renal impairment: A case report

Journal: South East Asia Journal of Medical Sciences

Article type: Research Article

Published: 2019-12-30

Volume: 3; Issue: 4; Pages: 5-6

ISSN: 2522-7165

DOI: 10.5281/zenodo.3723458

Article URL: https://journals.littlebaypublishers.com/article/article-1783008461592-883540470

PDF: https://journals.littlebaypublishers.com/article/article-1783008461592-883540470.pdf

JATS XML: https://journals.littlebaypublishers.com/article/article-1783008461592-883540470.xml

Authors

  1. Shakil Ahmed Chohan
    Changi General Hospital
    http://orcid.org/0000-0003-2532-8195
  2. Diraviyam Balasubramanian
    Changi General Hospital, Singapore
    https://orcid.org/0000-0003-0605-0685
  3. Thet Thet Soe
    Changi General Hospital
    https://orcid.org/0000-0002-1956-3538

Abstract

Colchicine is widely used in the treatment of acute gout. It has a narrow therapeutic window and can be extremely toxic in vulnerable older patients especially those with renal impairment. The most common side effects are gastrointestinal related, such as nausea, vomiting, diarrhea and abdominal pain. Colchicine-induced acute pancreatitis is very rare especially within therapeutic dose range. We report an atypical presentation of acute pancreatitis caused by a therapeutic dose of colchicine in an elderly patient with preexisting chronic renal disease.

Keywords

acute pancreatitis; atypical presentation; older person; colchicine-induced; renal impairment

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